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Continuing Transition to an Asset-Light Business Model to Improve Overall Efficiency Delivered Non-GAAP Operating Profitability in Both Q4'25 and FY'25 Generated Positive Operating Cash Flow for Both Q4'25 and FY'25 Continued Gross Profit Margin Expansion for B2B Business in Both Q4'25 and FY'25 SHANGHAI, April 9, 2026 /PRNewswire/ -- 111, Inc. ("111" or the "Company") (NASDAQ: YI), a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare industry by digitally empowering the upstream and downstream in China, today announced its unaudited financial results for the fourth quarter and fiscal year ended December 31, 2025. 2025 Executing Strategic Optimization: Embraces Asset-Light Partnership Network Growth In 2025, the Company proactively implemented strategic structural optimization by divesting its 100% equity interests in several subsidiaries.

Transition from An Asset-Heavy Business Model to An Asset-Light Business Model Achieved Quarterly Non-GAAP Net Profitability Maintained Non-GAAP Operational Profitability for Three Consecutive Quarter s Achieved Quarterly Positive Operating Cash Flow SHANGHAI , Dec. 17, 2025 /PRNewswire/ -- 111, Inc. ("111" or the "Company") (NASDAQ: YI), a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare industry by digitally empowering the upstream and downstream in China, today announced its unaudited financial results for the third quarter ended September 30, 2025. Third Quarter 2025 Highlights Total operating expenses were RMB180.3 million (US$25.3 million), representing a decrease of 13.4% compared to RMB208.2 million in the same quarter of last year.