(APLS)
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| Breakdown | |
|---|---|
| 13.74% | % of Shares Held by All Insider |
| 100.67% | % of Shares Held by Institutions |
| 116.71% | % of Float Held by Institutions |
| 374 | Number of Institutions Holding Shares |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Wellington Management Group, LLP | 12.72M | 2025-12-31 | 9.95% | $215.88M |
| Avoro Capital Advisors LLC | 12.22M | 2025-12-31 | 9.56% | $207.41M |
| Vanguard Group Inc | 10.67M | 2025-12-31 | 8.35% | $181.15M |
| Morgan Stanley | 9.17M | 2025-12-31 | 7.18% | $155.67M |
| Deep Track Capital, Lp | 7.75M | 2025-12-31 | 6.06% | $131.52M |
| RTW Investments LP | 7.67M | 2025-12-31 | 6.00% | $130.10M |
| Blackrock Inc. | 6.26M | 2025-12-31 | 4.90% | $106.23M |
| State Street Corporation | 4.61M | 2025-12-31 | 3.61% | $78.29M |
| UBS Group AG | 4.19M | 2025-12-31 | 3.27% | $71.04M |
| Suvretta Capital Management, LLC | 4.14M | 2025-12-31 | 3.24% | $70.25M |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| VANGUARD SPECIALIZED FUNDS-Vanguard Health Care Fund | 8.17M | 2025-10-31 | 6.39% | $138.72M |
| iShares Trust-iShares Core S&P Small-Cap ETF | 6.16M | 2026-01-31 | 4.82% | $104.59M |
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 3.39M | 2025-12-31 | 2.65% | $57.44M |
| SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF | 2.96M | 2026-01-31 | 2.32% | $50.28M |
| VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund | 2.44M | 2025-12-31 | 1.91% | $41.37M |
| Vanguard Explorer Fund | 1.43M | 2025-10-31 | 1.12% | $24.33M |
| VANGUARD INDEX FUNDS-Vanguard Small-Cap Growth Index Fund | 1.37M | 2025-12-31 | 1.08% | $23.33M |
| VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund | 1.11M | 2025-12-31 | 0.87% | $18.80M |
| SPDR SERIES TRUST-State Street SPDR Portfolio S&P 600 Small Cap ETF | 931,500 | 2026-01-31 | 0.73% | $15.81M |
| iShares Trust-iShares S&P Small-Cap 600 Growth ETF | 860,118 | 2026-01-31 | 0.67% | $14.60M |
| iShares Trust-iShares Biotechnology ETF | 765,654 | 2025-12-31 | 0.60% | $14.84M |
| iShares Trust-iShares Russell Mid-Cap Growth ETF | 744,232 | 2025-12-31 | 0.58% | $14.42M |
| Prudential Jennison Small Co Fd., Inc.-PGIM JENNISON SMALL COMPANY Fd. | 686,856 | 2025-09-30 | 0.54% | $13.98M |
| First TRT Exch-Trd AlphaDEX Fd.-First TRT Health Care AlphaDEX Fd. | 655,551 | 2026-01-31 | 0.51% | $12.70M |