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Nuvalent, Inc. (NUVL)
NGM – Real Time Price. Currency in USD
123.96
+123.96 (0.00%)
Market open: Jul 14, 2026, 4:00 PM EDT
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NGM – Real Time Price. Currency in USD
123.96
+123.96 (0.00%)
Market open: Jul 14, 2026, 4:00 PM EDT
Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are Zidesamtinib (NVL-520), a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the Phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; Neladalkib (NVL-655), a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the Phase 2 portion of the ALKOVE-1 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR that is in Phase 1a/1b clinical trial. Nuvalent, Inc. has a strategic partnership with Guardant Health, Inc. to develop companion diagnostics therapies. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.
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| Date | Type | Document |
|---|---|---|
| 2026-07-27 | 15-12G | d38689d1512g.htm |
| 2026-07-15 | POSASR | d190453dposasr.htm |
| 2026-07-07 | SC 14D9/A | d153608dsc14d9a.htm |
| 2026-06-24 | SC TO-T/A | d183214dsctota.htm |
| 2026-06-24 | SC TO-T | d90297dsctot.htm |
| 2026-06-18 | 8-K | nuvl-20260616.htm |
| 2026-06-09 | SC14D9C | d130887dsc14d9c.htm |
| 2026-06-09 | SC TO-C | d29899dsctoc.htm |
| 2026-06-09 | 8-K | d137459d8k.htm |
| 2026-05-07 | 8-K | nuvl-20260507.htm |