Denali Therapeutics Inc. (DNLI)

NMS – Real Time Price. Currency in USD

18.16

-1.57 (-7.98%)

At close: Mar 27, 2026, 4:00 PM EDT

18.28

+0.12 (0.66%)

After-hours: Mar 27, 2026, 6:55 PM EDT

About the company

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson’s and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company’s OTV programs also comprise DNL628 targeting tau for Alzheimer’s disease; and DNL422 targeting alpha synuclein for Parkinson’s disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer’s disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Key Executives

Name	Position
Dr. Alexander O. Schuth M.D., Ph.D.	Co-Founder, CFO, COO & Secretary
Dr. Dana Andersen	Chief Technical and Manufacturing Officer
Dr. Ryan J. Watts Ph.D.	Co-Founder, President, CEO & Director
Mr. Chris Walsh J.D.	General Counsel
Mr. Joe Lewcock Ph.D.	Chief Scientific Officer
Mr. Peter Chin M.D.	Acting Chief Medical Officer & Head of Development
Ms. Cindy Dunkle	Chief People Officer